Africa
Travel vaccinations for South Africa: requirements, recommendations and malaria in the Kruger area
Entry rules for South Africa: certificate only if arriving from a yellow fever area. The German Federal Foreign Office recommends Hepatitis A for all travellers, with further vaccines depending on your trip. Malaria: varies by region.
Editorial team promovax.eu · As of Oct 2026 · Sources: German Federal Foreign Office, WHO, DTG
South Africa at a glance
Entry: yellow fever certificate
Certificate only if arriving from a yellow fever area (from 1 year of age)
No yellow fever vaccination is required when travelling directly from Germany. Travellers arriving from a yellow fever country or after a transit of more than 12 hours there, for example in Nairobi or Addis Ababa, must show proof of vaccination; because of possible delays, the Foreign Office also recommends it for shorter transits through such a country.
Malaria
Varies by region
According to the Foreign Office the risk depends on region and season: in the north-east of Limpopo and Mpumalanga provinces, including Kruger National Park, it is high from September to May and moderate from June to August; in KwaZulu-Natal and the remaining parts of Limpopo and Mpumalanga it is low all year. The southern parts of the country are malaria-free. Discuss mosquito protection, possible prevention and, for remote areas, emergency standby treatment with a doctor.
Other health advice
- HIV is very widespread in South Africa; condoms protect during sexual contact.
- Schistosomiasis is transmitted in fresh water in Limpopo, Mpumalanga, KwaZulu-Natal and the Eastern Cape near Port Elizabeth.
- South Africa lies in a zone of increased UV radiation; sun protection matters even on coasts with a cool breeze.
- The Foreign Office advises drinking only water from a safe source and paying attention to food hygiene.
No doses or schedules: what applies to you is decided in a travel health consultation.
South Africa requires no vaccinations if you arrive directly from Germany. As a travel vaccination, the German Federal Foreign Office (Auswärtiges Amt) mainly recommends hepatitis A, with hepatitis B and rabies added for longer stays or particular exposure. Malaria only occurs in the north and north east, most intensely in the Kruger area between September and May. Cape Town, the Garden Route and the rest of the south are malaria-free.
Entry rules: yellow fever and transit
According to the Foreign Office, there are no mandatory vaccinations for direct arrival from Germany. South Africa itself is not a yellow fever country. Proof is required, however, if you arrive from a yellow fever country, and also if you spent more than 12 hours in transit there. The Foreign Office gives connections in Nairobi or Addis Ababa as examples. Because flights can be delayed and transit times cannot always be verified, it recommends vaccination even for shorter transits through such a country.
So if you fly via East Africa or combine South Africa with Kenya, discuss yellow fever vaccination early. The Foreign Office notes that a single vaccination is now accepted as lifelong proof for international travel. In Germany it is only given at approved yellow fever vaccination centres.
Recommended vaccinations according to the Foreign Office
The table at the top of this page summarises the classification. In context:
- All travellers: hepatitis A.
- Long stays or particular exposure: hepatitis B and rabies. The Foreign Office gives self-drive travellers camping, contact with wild animals and animal welfare project work as examples.
- Cholera: according to the Foreign Office only very rarely indicated, for example when working in a hospital with cholera patients.
- Routine vaccinations: check that you are up to date with the STIKO schedule, the official German vaccination calendar. Our guide to routine vaccinations for adults explains which ones apply.
Compared with many long-haul destinations, the vaccination effort for South Africa is modest. That makes it all the more worth looking at your route, because the differences between Cape Town and the Lowveld in the north east are considerable.
Malaria: where and when the risk exists
According to the Foreign Office and the DTG, malaria risk depends on region and season. More than 99 per cent of cases are falciparum malaria.
| Region | Malaria risk according to the Foreign Office |
|---|---|
| North-eastern Limpopo and Mpumalanga, including Kruger and neighbouring parks | high from September to May, moderate from June to August |
| KwaZulu-Natal, including iSimangaliso and Hluhluwe-iMfolozi | low all year round |
| Other parts of Limpopo and Mpumalanga, such as Waterberg, Marakele, Madikwe | low all year round |
| Southern regions, such as Cape Town and the Garden Route | malaria-free |
In risk areas, protect yourself consistently against mosquito bites, especially at dusk and at night, using repellent, long clothing and a bed net. For high-risk areas the Foreign Office also considers preventive medication useful. For moderate-risk areas more than 48 hours away from a facility able to diagnose malaria, it advises carrying medication for emergency standby treatment. Which approach suits your trip is something to decide with your doctor. Our guide to malaria prevention explains the background.
If you develop a fever after a trip to the north east, even months later, have malaria ruled out straight away and mention your journey.
What depends on your type of trip
| Type of trip | What matters most |
|---|---|
| City break in Cape Town or Johannesburg | Hepatitis A, routine vaccinations, food hygiene |
| Self-drive along the Garden Route | Malaria-free, sun protection, insurance with repatriation |
| Safari in the Kruger area | Seasonal malaria risk, mosquito protection, medical advice on prevention |
| Camping, self-drive, animal contact | Consider hepatitis B and rabies |
| Onward travel to Namibia or East Africa | Check yellow fever rules and malaria in neighbouring countries |
If you combine South Africa with Namibia, go through both countries together during your consultation.
HIV, water, bilharzia and sun
According to the Foreign Office, HIV is the biggest health problem in South Africa and is very widespread among adults. Condoms protect during sexual contact. Tuberculosis is mainly relevant for travellers in healthcare settings or during longer stays in crowded housing.
Diarrhoeal illness is among the most common travel complaints. The Foreign Office advises drinking only water from a safe source, never tap water, and paying attention to food and hand hygiene. Bilharzia (schistosomiasis) can be transmitted in fresh water in Limpopo, Mpumalanga, KwaZulu-Natal and in the Eastern Cape near Port Elizabeth, so do not swim in open fresh water there.
South Africa lies in a zone of increased UV radiation. Sun protection with a hat and high-factor sunscreen is important, even on coasts with a cool sea breeze.
Medical care in South Africa
The Foreign Office rates medical care as good overall. Private hospitals in the large cities are of European standard, state hospitals lag behind and care in rural areas is weaker. Payment upfront is generally required for treatment, sometimes in substantial amounts. Travel health insurance with repatriation cover is therefore strongly advised.
Timing and costs
Plan your travel health consultation a few weeks before departure. STIKO and DTG recommend completing travel vaccinations at least two weeks before you leave. You can find a suitable practice in Germany in our directory of travel clinics, and the travel vaccine check gives a first overview. What German statutory health insurers cover for private trips is explained in our guide to travel vaccination costs.
FAQ: South Africa
Do I need a yellow fever vaccination for South Africa?
Not if you arrive directly from Germany. According to the German Federal Foreign Office, proof is required if you arrive from a yellow fever country or spent more than 12 hours in transit there. Because of possible delays, the Foreign Office recommends vaccination even for shorter transits through such a country.
Is there malaria in Kruger National Park?
Yes. According to the Foreign Office and the German Society for Tropical Medicine (DTG), the risk in north-eastern Limpopo and Mpumalanga, including Kruger National Park, is high from September to May and moderate from June to August. Discuss mosquito protection and possible prevention with a doctor before you travel.
Do I need malaria protection for Cape Town and the Garden Route?
The Foreign Office describes the southern regions as malaria-free. Preventive medication is therefore not an issue there, as long as you do not travel on to the north or north east.
Which vaccinations do I need for a self-drive camping tour?
The Foreign Office explicitly names self-drive travellers camping as an example where hepatitis B and rabies should be considered in addition to hepatitis A. Your doctor will assess this based on your route.
Sources
- Auswärtiges Amt: Südafrika, Reise- und Sicherheitshinweise (Gesundheit) (as of 2026-10)
- WHO: Countries with risk of yellow fever transmission and countries requiring yellow fever vaccination (as of 2022-11)
- DTG: Empfehlungen zur Malariaprävention 2026 (as of 2026)
- RKI: Epidemiologisches Bulletin 27/2026, STIKO and DTG travel vaccination recommendations (as of 2026-07)
- WHO: International Travel and Health, Country List (vaccination requirements and WHO recommendations) (as of 18.11.2022 (revidiert 03.01.2023))